Endocrine Abstracts

Objective: We aimed to determine the risk of hypercalcemia in a geriatric population with very high dose levels of 25-hydroxy-vitamin D (25(OH)D)Patients and Method: This study was designed as a retrospective, cross-sectional two-center study for examining the elderly patients with very high 25(OH)D levels (>88ng/ml) between January 2014 and December 2019. After recruitment, subgroup analyses of the patients were performed based on their calcium and ...

Background: Acromegaly is associated with increased risk of coronary atherosclerosis and cardiovascular mortality. Changes in coagulation and fibrinolysis markers in acromegalic patients have been shown to indicate increase in the risk of developing cardiovascular disease. Mean platelet volume (MPV) is a marker of platelet functions and activity, and increased MPV is an independent risk factor of myocardial infarction and thrombotic events. In this study, we examined the level...

Introduction: Differentiated thyroid carcinoma (DTC) rarely represents with distant organ metastasis. Cerebral metastasis is seen in 0.4–1.2% of patients with distant organ metastasis. There are only 14 patients of DTC with pituitary metastasis reported in the literature. Here, we report a papillary thyroid carcinoma (PTC) patient represented with pituitary metastasis.Case: A 68-year-old male patient has admitted to our hospital with a growing tumou...

ABSTRACT WITHDRAWN...

Aim: Metabolic syndrome rates have been studied especially in adrenal gland secreting cortisol and studies on nonfunctional adenomas are limited. In this study, we investigated metabolic parameters and metabolic syndrome frequency in non-functional adrenal adenomas (NFA).Materials and methods: In our study, 55 patients (15 men (27.3%), 40 women (72.7%) who were diagnosed incidentally, unilateral or bilateral localized, hormone-inactive, and with adenoma-...

Introduction: Hyperkalemia due to zona glomerulosa (ZG) insufficiency is generally transient and mild for patients with aldosterone-producing adenoma (APA) after adrenalectomy. We report here a case with prolonged ZG insuffiency requiring long-term mineralocorticoid replacement (MR) therapy.Case report: A 45-years-old female with hypertension and hypokalemia admitted to outpatient clinic with incidentally detected right adrenal adenoma (3 cm) showing sig...

Introduction: Hypogonadism persisting in man with macroprolactinoma requires exogenous testosterone replacement therapy (TRT). But TRT may cause secondary elevations of prolactin. We report here a case of macroprolactinoma and hypogonadotropic hypogonadism with persistently high prolactin level after initiating TRT.Case report: A 28 year-old male was admitted to outpatient clinic with complaints of headache, low libido and blurred vision on left eye for ...

Introduction: Ectopic ACTH syndrome (EAS) is a rare cause of Cushing’s syndrome. EAS is most frequently caused by bronchial carcinoid tumor or small cell lung cancer. Medullary thyroid carcinoma (MTC) is a rare source of EAS, as reported in this case.Case report: A 65-years-old-female with back pain and weight gain referred to our outpatient clinic with determined signs and symptoms of hypercortisolism. She had arterial hypertension, her sister had ...

Introduction: Cushing’s disease (CD) frequently leads to hypogonadotropic hypogonadism by hypercortisolism and hyperandrogenemia. In the literature, there are totally 96 cases of CD and pregnancy. Only four of 11 cases, operated transsphenoidally, were cured. We aimed to present a case of CD developing pregnancy in which hypercortisolism was successfully controlled by transsphenoidal surgery (TSS) in 2nd trimester.Case report: 28 years old female wa...

Introduction: Maturity-onset diabetes of young (MODY) type 2 is caused by mutation of the glucokinase gene. It is characterized by mild fasting hyperglicemia and absence of vascular complications. It is estimated that the incidence of gestational diabetes is 3%. We aimed to present a pregestational diabetic case with MODY-type 2 in pregnancy.Case report: A 38-year-old pregnant woman was referred to our clinic for glycemic regulation at 22th week of gesta...